Is There a Cause for ADHD?

With rates of diagnosis rising, the origins of ADHD have come under scrutiny. Researchers haven't identified a single, definitive cause for ADHD.

ADHD is likely caused by a complex interplay of factors. Genetics, environment, brain changes, and prenatal risks. If a close family member has ADHD, you're more likely to have it. Twin and adoption studies suggest genetics contribute to about 75% of ADHD cases.

However, genetics is not the only determining factor. Environmental exposures, brain injuries, prenatal conditions, exposure to environmental toxins, and social/family environment can also contribute to the development of ADHD.

Complications during pregnancy or delivery, like low birth weight or preterm birth, may contribute to the development of ADHD. These prenatal risks suggest that events in the earliest stages of brain development could play a role. While researchers have identified many risk factors, there is no single cause of ADHD.

ADHD arises from a combination of genetic vulnerabilities and environmental influences, all of which affect early brain development. Understanding these complex interactions can help inform more effective treatment and prevention strategies.

Specific Genes Linked to ADHD

man with random thoughts

Certain genes have been linked to a higher risk of developing ADHD. The genes DRD4, DRD5, DAT1, 5HTT, and SNAP25 regulate dopamine and serotonin, two important neurotransmitters for attention and focus. Variations in these genes may lead to lower levels or reuptake of these neurotransmitters, contributing to the symptoms of ADHD.

Research on siblings and twins suggests that genetics contribute to ADHD. Siblings of children with ADHD have a higher risk of also having the disorder. Identical twins share very similar genes, so they are more likely to both have ADHD compared to fraternal twins, who share about 50% of their genes.

Brain Development

Research shows that ADHD may be linked to certain changes in brain development. Studies using imaging scans show that children and adolescents with ADHD have some differences in brain development compared to those without the condition. Specifically, certain areas of the brain that are important for attention and self-control seem to develop more slowly. The frontal lobes, which are involved in controlling attention and impulses, appear to mature later in children with ADHD. The connections between the frontal lobes and other brain networks are also altered or delayed.

These brain changes are thought to impact functioning in attention, organization, planning, and self-regulation. However, the exact causes of these developmental differences remain unknown. While these findings point to biological bases for ADHD symptoms, it is important to note that a diagnosis of ADHD is based on a consistent pattern of behavior, not on brain scans alone. Not all children with differences in brain development will meet the criteria for an ADHD diagnosis. Likewise, not all children with ADHD will show the same patterns of brain development.

Environmental Factors

Exposure to environmental toxins like lead, mercury, and organophosphates during prenatal and early childhood development may influence the risk of developing ADHD. A diet high in processed foods, sugar, and additives may also play a role in the development of ADHD.

Conversely, deficiencies in certain nutrients, such as omega-3 fatty acids, zinc, and magnesium, may also contribute to symptoms of inattention and hyperactivity. A balanced diet with whole foods and limiting excess sugar intake could help support optimal brain development and functioning.

Excessive exposure to television, video games, and other electronic media, especially during early childhood, may play a factor in the development of ADHD. The fast-paced nature and constant stimulation provided by media can condition the brain to expect high arousal and make it difficult to focus in less stimulating environments like the classroom.  

ADHD is a heterogeneous disorder, meaning that many possible pathways can lead to the condition. More research is still needed to fully understand ADHD's origins. If you're wondering if you may have ADHD or know someone who has it, we can help you. Reach out to us to book an appointment for conflict resolution session with us today.